Arsenal will face Wigan in the FA Cup fourth round, while Chelsea have been handed a showdown with Liam Rosenior’s former club, Hull.
The Gunners, who beat Portsmouth 4-1 in the third round, will take on Wigan at the Emirates Stadium in a repeat of the 2014 final which saw the north London outfit end their long wait for a major trophy.
Chelsea, meanwhile, will travel to the MKM Stadium as new head coach Rosenior comes up against the club he played for and managed.
Macclesfield FC’s reward for knocking out holders Crystal Palace is another home tie against another side from the capital as Keith Andrews’ in-form Brentford will seek to avoid becoming victims of an FA Cup shock.
Liverpool host Barnsley on Monday evening and will face Brighton – who beat Manchester United at Old Trafford on Sunday – in round four should they overcome the League One side.
Manchester City will have to wait a week to discover their fourth round opponents as the Salford vs Swindon tie has been rearranged for January 20 after their clash on Saturday was postponed because of a frozen pitch.
Aston Villa will welcome fellow Premier League opposition in Newcastle to Villa Park in arguably the standout tie from the FA Cup fourth round draw.
FA Cup fourth round draw in full
Liverpool or Barnsley vs Brighton
Stoke vs Fulham
Oxford United vs Sunderland
Southampton vs Leicester
Wrexham vs Ipswich
Arsenal vs Wigan
Hull vs Chelsea
Burton vs West Ham
Burnley vs Mansfield
Norwich vs West Brom
Port Vale vs Bristol City
Grimsby vs Wolves
Aston Villa vs Newcastle
Man City vs Salford or Swindon
Macclesfield FC vs Brentford
Birmingham vs Leeds
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